Ecclesiastical Minefields by Ian Outerbridge, et al.

"Viable Offspring Derived from Fetal and Adult Mammalian Cells" (1997), by Ian Wilmut et al

In the 1990s, Ian Wilmut [3], Jim McWhir, and Keith Campbell performed experiments while working at the Roslin Institute in Roslin, Scotland. Wilmut, McWhir, and Campbell collaborated with Angelica Schnieke and Alex J. Kind at PPL Therapeutics in Roslin, a company researching cloning [4] and genetic manipulation for livestock. Their experiments resulted in several sheep [5] being born in July 1...

Response by Caplan et al.

W e would like to thank Dr. Wong for the response to our article “No time to waste—the ethical challenges created by CRISPR”. Dr. Wong’s letter addresses a question about the relationship between biology and society: that “prevailing papers” on CRISPR-Cas9 rarely emphasize understanding the microbiological processes that make CRISPR-Cas9 an effective defensive mechanism. Instead, scientists and...

Comment on papers by Chong et al., Nishio et al., and Suri et al. on diabetes reversal in NOD mice.

Chong et al., Nishio et al., and Suri et al. (Reports, 24 March 2006, pp. 1774, 1775, and 1778) confirmed that treating nonobese diabetic (NOD) mice with an immune adjuvant and semisyngenic spleen cells can reverse the disease but found that spleen cells did not contribute to the observed recovery of pancreatic islets. We show that islet regeneration predominately originates from endogenous cel...

Reply to R.L. Bowen et al, M. Froehner et al, J.L. Leow et al, and C. Brady et al.

Regarding our article on the association of androgen deprivation therapy (ADT) with increased Alzheimer’s disease risk, Bowen et al, Froehner and Wirth, Leow et al, and Brady et al highlight a number of significant considerations that will prove important in the design of future studies that investigate the association of ADT and Alzheimer’s disease. We agree with Bowen et al and Leow et al tha...

In Response to Murphy et al., Löwer et al., and Lan et al